Azelaic Acid

activeCAS: 123-99-9

Multi-functional active safe for pregnancy. Addresses acne, rosacea, and pigmentation. Antibacterial and anti-inflammatory.

Safety Ratings

Safety5/5
Comedogenic0/5
Irritancy1/5
EWG Score2/10

Skin Type Compatibility

oily
5/5
dry
4/5
sensitive
4/5
combination
5/5
normal
5/5

Addresses Concerns

acnerosaceapigmentationrednesstexture

Functions

brighteninganti-acneanti-inflammatoryantioxidant

Known Interactions

synergy
Niacinamide

Azelaic acid provides anti-inflammatory, antibacterial, and tyrosinase-inhibiting effects, while niacinamide inhibits melanosome transfer and strengthens the barrier. Together they are highly effective for rosacea, acne, and post-inflammatory hyperpigmentation.

synergy
Retinol

Azelaic acid and retinol target skin concerns through different pathways. Azelaic acid is anti-inflammatory and inhibits abnormal melanocyte activity, while retinol increases cell turnover. Together they are effective for acne and hyperpigmentation without excessive irritation, as azelaic acid is generally well-tolerated.

synergy
Salicylic Acid

Azelaic acid provides anti-inflammatory and antibacterial benefits while salicylic acid clears pores with oil-soluble exfoliation. This combination targets acne from multiple angles without excessive irritation, as azelaic acid is relatively gentle.

synergy
Ascorbic Acid

Azelaic acid and ascorbic acid both inhibit melanin production through different mechanisms. Azelaic acid targets abnormal melanocytes while ascorbic acid is a broad tyrosinase inhibitor. Together they provide powerful brightening for melasma and post-inflammatory hyperpigmentation.

Products Containing This Ingredient

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